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期刊论文 14

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2020 1

2019 2

2017 1

2015 2

2010 3

2009 1

2007 2

2001 1

2000 1

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关键词

压力容器技术 2

抑爆抗爆 2

亚细胞定位 1

交错缠绕 1

人造细菌鞭毛（ABFs） 1

全双层 1

全双层结构 1

初生多肽相关复合物 1

功能化 1

可游动微纳米机器人 1

基于应变的设计 1

基因敲除 1

复合薄内筒 1

多功能壳 1

小麦赤霉病 1

止裂韧性 1

油气管道 1

生物医学应用 1

磁控螺旋形微纳米机器人 1

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Gene delivery into isolated

Nan Zheng, Ziyuan Song, Yang Liu, Lichen Yin, Jianjun Cheng

《化学科学与工程前沿（英文）》 2017年第11卷第4期页码 521-528 doi: 10.1007/s11705-017-1612-8

摘要： The application of gene delivery materials has been mainly focused on mammalian cells while rarely extended to plant engineering. Cationic polymers and lipids have been widely utilized to efficiently deliver DNA and siRNA into mammalian cells. However, their application in plant cells is limited due to the different membrane structures and the presence of plant cell walls. In this study, we developed the cationic, -helical polypeptide that can effectively deliver DNA into both isolated protoplasts and intact leaves. The PPABLG was able to condense DNA to form nanocomplexes, and they exhibited significantly improved transfection efficiencies compared with commercial transfection reagent Lipofectamine 2000 and classical cell penetrating peptides such as poly(L-lysine), HIV-TAT, arginine9, and poly(L-arginine). This study therefore widens the utilities of helical polypeptide as a unique category of gene delivery materials, and may find their promising applications toward plant gene delivery.

关键词： α-helical polypeptide plant gene delivery protoplast intact leaves transfection

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Closed surface modeling with helical line measurement data

LI Ruqiong, LI Guangbu, WANG Yuhan

《机械工程前沿（英文）》 2007年第2卷第1期页码 72-76 doi: 10.1007/s11465-007-0012-z

摘要： Models for surface modeling of free-form surface and massive data points are becoming an important feature in commercial computer aided design/computer-aided manufacturing software. However, there are many problems to be solved in this area, especially for closed free-form surface modeling. This article presents an effective method for cloud data closed surface modeling from asynchronous profile modeling measurement. It includes three steps: first, the cloud data are preprocessed for smoothing; second, a helical line is segmented to form triangle meshes; and third, Bezier surface patches are created over a triangle mesh and trimmed to shape on an entire surface. In the end, an illustrative example of shoe last surface modeling is given to show the availability of this method.

关键词： free-form surface helical triangle design/computer-aided manufacturing effective

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Characteristics of flow and heat transfer of shell-and-tube heat exchangers with overlapped helical baffles

Tingting DU, Wenjing DU

《工程管理前沿（英文）》 2019年第6卷第1期页码 70-77 doi: 10.1007/s42524-019-0005-8

摘要：

The characteristics of flow and heat transfer of shell-and-tube heat exchangers with overlapped helical baffles (STHXsHB) were illustrated through a theoretical analysis and numerical simulation. The ideal helical flow model was constructed to demonstrate parts of the flow characteristics of the STHXsHB, providing theoretical evidence of short-circuit and back flows in a triangular zone. The numerical simulation was adopted to describe the characteristics of helical, leakage, and bypass streams. In a fully developed section, the distribution of velocity and wall heat transfer coefficient has a similar trend, which presents the effect of leakage and bypass streams. The short-circuit flow accelerates the axial velocity of the flow through the triangular zone. Moreover, the back flow enhances the local heat transfer and causes the ascent of flow resistance. This study shows the detailed features of helical flow in STHXsHB, which can inspire a reasonable optimization on the shell-side structure.

关键词： heat exchanger overlapped helical baffle triangular zone helical flow

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CFD simulation on shell-and-tube heat exchangers with small-angle helical baffles

Minhua ZHANG,Fang MENG,Zhongfeng GENG

《化学科学与工程前沿（英文）》 2015年第9卷第2期页码 183-193 doi: 10.1007/s11705-015-1510-x

摘要： Shell-and-tube heat exchanger with helical baffles is superior to that with segmental baffles in reducing pressure drop, eliminating dead zone and lowering the risks of vibration of tube bundle. This paper focused on the small-angle helical baffles that have been merely reported in open literature. These baffles are noncontinuous helical baffles with a helix angle of 10° to 30°, and their shapes are 1/4 ellipse, 1/4 sector and 1/3 sector. To assess the integrative performance, /? is employed, and the calculated results show that among the three baffle shapes the heat exchangers with a 1/4 sector helical baffle have the lowest pressure drop. At = 10° and 20°, 1/4 sector helical baffle heat exchangers show the best integrative performance; at = 30°, 1/4 ellipse and 1/4 sector helical baffle heat exchangers perform almost the same. For the study of helix angles, we found that 30° has the best integrative performance at low mass flow rate, almost the same as 20° at high mass flow rate.

关键词： heat transfer pressure drop helical baffle CFD

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Convective heat transfer in helical coils for constant-property and variable-property flows with high

Yufei MAO, Liejin GUO, Bofeng BAI, Ximin ZHANG

《能源前沿（英文）》 2010年第4卷第4期页码 546-552 doi: 10.1007/s11708-010-0116-8

摘要： Forced convection heat transfer of single-phase water in helical coils was experimentally studied. The testing section was constructed from a stainless steel round tube with an inner diameter of 10 mm, coil diameter of 300 mm, and pitch of 50 mm. The experiments were conducted over a wide Reynolds number range of 40000 to 500000. Both constant-property flows at normal pressure and variable-property flows at supercritical pressure were investigated. The contribution of secondary flow in the helical coil to heat transfer was gradually suppressed with increasing Reynolds number. Hence, heat transfer coefficients of the helical tube were close to those of the straight tube under the same flow conditions when the Reynolds number is large enough. Based on the experimental data, heat transfer correlations for both incompressible flows and supercritical fluid flows through helical coils were proposed.

关键词： convective heat transfer helical coils high Reynolds number supercritical pressure variable property

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Cutting Force Model for a Small-diameter Helical Milling Cutter

LI Xiwen, YANG Shuzi, YANG Mingjin, XIE Shouyong

《机械工程前沿（英文）》 2007年第2卷第3期页码 272-277 doi: 10.1007/s11465-007-0047-1

摘要： In the milling process, the major flank wear land area (two-dimensional measurement for the wear) of a small-diameter milling cutter, as wear standard, can reflect actual changes of the wear land of the cutter. By analyzing the wearing characteristics of the cutter, a cutting force model based on the major flank wear land area is established. Characteristic parameters such as pressure parameter and friction parameter are calculated by substituting tested data into their corresponding equations. The cutting force model for the helical milling cutter is validated by experiments. The computational and experimental results show that the cutting force model is almost consistent with the actual cutting conditions. Thus, the cutting force model established in the research can provide a theoretical foundation for monitoring the condition of a milling process that uses a small-diameter helical milling cutter.

关键词： computational corresponding helical milling theoretical foundation Characteristic

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Geometric optimization model for the solar cavity receiver with helical pipe at different solar radiation

Chongzhe ZOU, Huayi FENG, Yanping ZHANG, Quentin FALCOZ, Cheng ZHANG, Wei GAO

《能源前沿（英文）》 2019年第13卷第2期页码 284-295 doi: 10.1007/s11708-019-0613-3

摘要： In consideration of geometric parameters, several researches have already optimized the thermal efficiency of the cylindrical cavity receiver. However, most of the optimal results have been achieved at a fixed solar radiation. At different direct normal irradiance (DNI), any single optimal result may not be suitable enough for different regions over the world. This study constructed a 3-D numerical model of cylindrical cavity receiver with DNI variation. In the model of a cylindrical cavity receiver containing a helical pipe, the heat losses of the cavity and heat transfer of working medium were also taken into account. The simulation results show that for a particular DNI in the range of 400 W/m to 800 W/m , there exists a best design for achieving a highest thermal efficiency of the cavity receiver. Besides, for a receiver in constant geometric parameters, the total heat losses increases dramatically with the DNI increasing in that range, as well as the temperature of the working medium. The thermal efficiency presented a different variation tendency with the heat losses, which is 2.45% as a minimum decline. In summary, this paper proposed an optimization method in the form of a bunch of fitting curves which could be applied to receiver design in different DNI regions, with comparatively appropriate thermal performances.

关键词： cylindrical cavity receiver 3-D numerical simulation geometric optimization direct normal irradiation

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Simultaneous acquisition of CT angiography and whole brain CT perfusion images by using multiphase dynamic helical

Weiwei CHEN, Jianpin QI, Wenzhen ZHU, Wenhua HUANG, Jinmei SONG

《医学前沿（英文）》 2009年第3卷第2期页码 230-235 doi: 10.1007/s11684-009-0023-8

摘要： We implemented a new protocol — multiphase dynamic helical scan to acquire CT angiography (CTA) and whole brain CT perfusion (CTP) images simultaneously with single scan on 16 multidetector CT (MDCT). A total of 90 patients who were randomly assigned into 3 groups were included in our study. Each group underwent CT scan by using the new protocol, traditional CTA and CTP protocol, respectively. The image quality of CTA, the CTP parameter values and the X-ray doses were measured and compared between the new protocol and the traditional protocols. There was no statistically significant difference in the CTA image quality between the above methods ( =0.55). For CTP parameters, the new protocol tended to overestimate the blood volume (BV) and blood flow (BF) value, and to underestimate the mean transit time (MTT) value compared with the traditional method. However, there was no statistically significant difference in BV, BF, and MTT value between the two methods except permeability surface (PS) ( >0.05). The volume CT dose index (CTDIvol) and dose length product (DLP) of our protocol were lower than the traditional one. The new protocol can obtain valuable diagnostic information in a shorter time without significant compromise in image quality. In addition, it reduces the radiation dose as well as contrast medium usage on the patient.

关键词： computed tomography angiography computed tomography perfusion

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初生多肽相关复合物调控小麦禾谷镰刀菌生长发育和致病性 Article

王旭丽, 谢鑫, 刘敬, 王国梁, 邱德文

《工程（英文）》 2020年第6卷第5期页码 546-552 doi: 10.1016/j.eng.2019.07.025

摘要：

对植物病原菌而言，维持蛋白质内稳态对其生存和繁殖至关重要。然而，当前对参与维持蛋白质内稳态的因子在真菌致病过程中的作用仍缺乏科学的认识。在本研究中，我们鉴定了十大病原真菌之一—禾谷镰刀菌（Fusarium graminearum）的初生多肽相关复合物（FgNAC）的功能。研究发现，FgNAC中的α亚基（FgNACα）与其在酵母和其他物种中的同源基因在结构和功能方面表现出高度相似性。禾谷镰刀菌NACα缺失突变体虽可存活但其菌丝生长、分生孢子产生和致病性受到严重削弱。此外，通过酵母双杂交实验发现FgNACα可以和FgNACβ亚基发生互作。亚细胞定位结果表明FgNACα和FgNACβ主要发生在细胞质中。未来的研究应致力于解析初生多肽相关复合物调节蛋白质代谢从而调控真菌发育和致病性的作用机制。

关键词：小麦赤霉病初生多肽相关复合物基因敲除致病性亚细胞定位

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磁控螺旋形微纳米机器人在生物医学方面的应用 Review

邱发敏, Bradley J. Nelson

《工程（英文）》 2015年第1卷第1期页码 21-26 doi: 10.15302/J-ENG-2015005

摘要：

磁控螺旋形微纳米机器人可在低强度旋转磁场（<10 mT）的驱动下，实现亚微米精度的三维（3D）游动。由于低强度磁场对细胞和组织无害，磁控螺旋形微纳米机器人在生物医学方面有很大的应用前景，如微创手术、细胞操作和分析以及靶向治疗。本文系统介绍了磁控螺旋形微纳米机器人的制造方法、运动控制和生物医学应用。

关键词：磁控螺旋形微纳米机器人可游动微纳米机器人人造细菌鞭毛（ABFs）功能化生物医学应用

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中国开创的抗爆钢复合材料压力容器技术

朱国辉

《中国工程科学》 2000年第2卷第6期页码 8-11

摘要：

压力容器是一种应用广泛的重要工程装置。大型压力贮罐、氨合成塔、尿素合成塔、石油加氢反应器、导弹壳体和液氢、液氧燃料压力容器，以及核堆压力壳等是国际上公认的高科技重大承压装备。纤维复合材料和普通钢制是当今世界压力容器技术的两大种类。作者开创了一种新的具有优良综合特性，已含国家发明奖励和18项中美专利成果的抗爆钢复合材料压力容器技术，使压力容器的使用安全性和制造经济性发生了极大的变革；其典型代表钢带缠绕式压力容器，已被美国机械工程师学会正式列入ASME标准，居国际领先水平，将为21世纪国际压力容器的设计、制造和安全保障技术的发展开创出新的局面。

关键词：压力容器技术纤维复合材料钢复合材料复合薄内筒交错缠绕全双层结构抑爆抗爆

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钢复合结构压力容器技术

朱国辉,朱立,郑津洋,郑传祥,陈志平,吴红梅

《中国工程科学》 2001年第3卷第7期页码 79-84

摘要：

对压力容器设计提出了一种技术先进的多功能壳和长远发展根本要求的新理念，并介绍了钢复合结构压力容器技术的四项新的专利技术发展体系。钢复合结构压力容器技术是一种国际创新的，涵盖各种高、中、低压，应用范围广阔的压力容器新技术。其主要特点是具抑爆抗爆、简化制造、分散缺陷和可实现经济可靠的在线安全状态自动监控等多功能壳特性，可降低制造成本30%～50%。

关键词：压力容器技术钢复合结构多功能壳钢带错绕全双层抑爆抗爆

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高钢级钢管和高压输送：我国油气输送管道的重大技术进步

李鹤林,吉玲康,田伟

《中国工程科学》 2010年第12卷第5期页码 84-90

摘要：

近年来，我国管道企业和相关科研院所联合攻关，取得了一批关键技术成果，这些成果包括：研制了X70，X80钢级高性能管线钢及焊管、管件；突破国际上螺旋缝埋弧焊管的使用禁区，确立了具有中国特色的“大口径高压输送主干线螺旋埋弧焊管与直缝埋弧焊管联合使用”的技术路线；在国内首次研究了高压输气管道动态断裂与止裂问题，采用Battelle双曲线模型预测了西气东输和西气东输二线等管道延性断裂的止裂韧性；在国内首次研究了油气管道基于应变的设计方法，解决了该设计方法及抗大变形管线钢管在强震区和活动断层管段应用的技术难题；解决了高强度焊管的腐蚀控制和应变时效控制等技术。

关键词：油气管道管线钢螺旋缝埋弧焊管止裂韧性基于应变的设计

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Genetic variants in the ADD1 and GNB3 genes and blood pressure response to potassium supplementation

Dai-Hai YU PhD, Jian-Feng HUANG MD, Ji-Chun CHEN MS, Jie CAO MS, Shu-Feng CHEN PhD, Dong-Feng GU MD, PhD, for the GenSalt Collaborative Research Group, De-Pei LIU PhD, Lai-Yuan WANG PhD, Jing CHEN MD, MSc, Jiang HE MD, PhD, Cashell E. JAQUISH PhD, Dabeeru C. RAO PhD, Charles GU PhD, James E. HIXSON PhD, Chung-Shiuan CHEN MS⁸, Paul K. WHELTON MD, MSc⁹,

《医学前沿（英文）》 2010年第4卷第1期页码 59-66 doi: 10.1007/s11684-010-0015-8

摘要： Dietary potassium-supplementation has been associated with a decreased risk of hypertension and other cardiovascular outcomes. However, blood pressure (BP) responses to potassium supplementation vary among individuals. This study was designed to examine the association between 12 single nucleotide polymorphisms (SNPs) in the adducin 1 alpha (ADD1) and guanine nucleotide binding protein (G protein) beta polypeptide 3 (GNB3) genes and systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) responses to potassium-supplementation. We conducted a 7-day high-sodium intervention (307.8 mmol sodium/day) followed by a 7-day high-sodium with potassium-supplementation (60 mmol potassium/day) among 1906 Han Chinese participants from rural north China. BP measurements were obtained at the end of each intervention period using a random-zero sphygmomanometer. We identified significant associations between ADD1 variant rs17833172 and SBP, DBP, and MAP responses to potassium-supplementation (all <0.0001) that remained significant after adjustment for multiple comparisons. In participants that were heterozygous or homozygous for the G allele of this marker, SBP, DBP, and MAP response to potassium-supplementation were −3.52 (−3.82, −3.21), −1.41 (−1.66, −1.15) and −2.12 (−2.37, −1.87), respectively, as compared to the corresponding responses of 1.99 (0.25, 3.73), −0.65 (−0.10, −0.21), and −0.23 (−0.37, 0.83), respectively, for those who were homozygous for A allele. In addition, participants with at least one copy of the G allele of rs12503220 of the ADD1 gene had significantly increased DBP and MAP response to potassium-supplementation ( = 0.0041 and 0.01, respectively), which was also significant after correction for multiple testing. DBP and MAP responses to potassium-supplementation were −1.36 (−1.63, −1.10) and −2.07 (−2.32, −1.82) for those with at least G allele compared to corresponding responses of 0.86 (−0.68, 2.40) and −0.45 (−1.74, 0.84) for those who were homozygous for A allele. In summary, our study identified novel associations between genetic variants of the ADD1 gene and BP response to potassium-supplementation, which could have important clinical and public health implications. Future studies aimed at replicating these novel findings are warranted.

关键词： blood pressure genetics polymorphism die-tary potassium potassium sensitivity adducin 1 alpha (ADD1) guanine nucleotide binding protein beta polypeptide 3 (GNB3)